脑诱发电位辅助诊断阿尔茨海默病和精神分裂症价值研究

The clinical applications of brain evoked potentials for the diagnosis of Alzheimers disease and schizophrenia.

目的探讨脑诱发电位（ｂｒａｉｎｅｖｏｋｅｄｐｏｔｅｎｔｉａｌｓ，ＢＥＰｓ）对阿尔茨海默病（Ａｌｚｈｅｉｍｅｒｓｄｉｓｅａｓｅ，ＡＤ）和精神分裂症的辅助诊断价值。方法应用逐步判别分析法，分析３９例ＡＤ、３２例老年慢性精神分裂症患者和４０例正常人的４项ＢＥＰｓ主成分指标。结果４项ＢＥＰｓ均有指标入选判别方程。ＢＥＰｓ指标在正常人组和ＡＤ组间的判别准确性为９３８５％；在正常人组和精神分裂症组间的判别准确性为９５７１％；在２组患者间的判别准确性为８８８９％；在三组被试者间的判别准确性为８５５７％。结论脑诱发电位对临床诊断Ａｌｚｈｅｉｍｅｒ病和精神分裂症有参考价值。

Objective To investigate the clinical significance of brain evoked potentials(BEPs)in the diagnosis of Alzheimers disease(AD) and schizophrenia.Methods The BEPs data were obtained from 39 AD patients, 32 chronic schizophrenics and 40 normal controls.A stepwise discriminant analysis was carried out based on all data.Results In the data of BEPs,the AD patients could be distinguished from normal controls with a accuracy of 93 85%, and the schizophrenics could be disungushed from normal controls with a accuracy of 88.89%.Among the 3 groups,one could be also distinguished from another with a accuracy of 85 57% in the data of BEPs.Conclusions BEPs are helpful for the diagnosis of Alzheimers diaease and schizophrenia.