期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

大疱性类天疱疮患者血清与疱液中巨噬细胞游走抑制因子的检测 被引量：2

原文传递
导出
摘要 目前认为大疱性类天疱疮（BP）的发病不仅与自身抗体的产生有关,而且与细胞因子网络的紊乱密切相关.巨噬细胞游走抑制因子（macrophage migration inhibitory factor,MIF）作为一种前炎症因子,在细胞因子网络平衡中发挥一定作用.本研究采用ELISA方法检测BP患者活动期血清、疱液中MIF的含量和缓解期血清中MIF的含量,以探讨MIF在BP发病机制中的作用及其临床意义.
作者 马蕾 黄萍
机构地区 滨州医学院附属医院皮肤科 沈阳市第七人民医院皮肤科
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2010年第6期422-422,共1页 Chinese Journal of Dermatology
基金 山东滨州医学院科研启动基金（BY2009KYQD03）
关键词 巨噬细胞游走抑制因子 大疱性类天疱疮 血清 检测 疱液 患者 细胞因子网络 ELISA方法
分类号 R758.66 [医药卫生—皮肤病学与性病学]
  • 相关文献

参考文献5

  • 1冯素英,靳培英,林麟,吴勤学,周武庆,桑红桂.大疱性类天疱疮疾病严重程度与BP180抗体水平关系的研究[J].中华皮肤科杂志,2007,40(4):199-201. 被引量：6
  • 2Shimizu T.Abe R,Ohkawara A,el al.Macrophage migration inhibitory factor is an essential immunoregulatory cytokine in atopic dermatitis.Biochem Biophys Res Commun,1997,240(1):173-178.
  • 3Shimizu T,Nishihira J,Mizue Y,et al.High macrophage migration inhibitory factor (MIF) serum levels associated with extended psoriasis.J Invest Dermatol,2001,116(6):989-990.
  • 4Foote A,Briganti EM,Kipen Y,el al.Macrophage migration inhibitory factor in systemic lupus erythematosus.J Rheumatol,2004,31(2):268-273.
  • 5Asano Y,Makino T,Norisugi Q,el al.Macrophage migration inhibitory factor (MIF) in bullous pemphigoid.J Dermatol Sci,2008,49(1):95-97.

二级参考文献9

  • 1冯素英,吴勤学,林麟,靳培英,周武庆,桑红桂.BP180NC16a—ELISA对大疱性类天疱疮血清学诊断的评价[J].中华皮肤科杂志,2007,40(1):10-12. 被引量：2
  • 2Giudice GJ,Emery DJ,Zelickson BD,et al.Bullous pemphigoid and herpes gestationis autoantibodies recognize a common noncoflagenous site on the BP180 ectodomain.J Immunol,1993,151(10):5742-5750.
  • 3Giudice GJ,Wilske KC,Anhalt GJ,et al.Development of an ELISA to detect anti-BP180 autoantibodies in bullous pemphigoid and herpes gestationis.J Invest Dermatol,1994,102(6):878-881.
  • 4Nakatani C,Muramatsu T,Shirai T.Immunoreactivity of bullous pemphigoid (BP)autoantibodies against the NC16A and C-terminal domains of the 180 kDa BP antigen(BP180):immunoblot analysis and enzyme-linked immunosorbent assay using BP180 recombinant proteins.Br J Dermatol,1998, 139(3 ): 365-370.
  • 5Tsuji-Abe Y,Akiyama M,Yamanaka Y,et al.Correlation of clinical severity and ELISA indices for the NC16A domain of BP180 measured using BP180 ELISA kit in bullous pemphigoid.J Dermatol Sci,2005, 37(3 ): 145-149.
  • 6Schmidt E,Obe K,Brocker EB,et al.Serum levels of autoantibodies to BP180 correlate with disease activity in patients with bullous pemphigoid.Arch Dermatol,2000, 136(2): 174-178.
  • 7Amo Y,Ohkawa T,Tatsuta M,et al.Clinical significance of enzymeliked immunosorbent assay for the detection of circulating anti-BP180 autoantibodies in patients with bullous pemphigoid.J Dermatol Sci, 2001. 26(1): 14-18.
  • 8Kobayashi M,Amagai M,Kuroda-Kinoshita K,et al.BP180 ELISA using bacterial recombinant NC16a protein as a diagnostic and monitoring tool for bullous pemphigoid.J Dermatol Sci, 2002. 30(3): 224-232.
  • 9Mariotti F,Grosso F,Terracina M,et al.Development of a novel ELISA system for detection of anti-BP180 IgG and characterization of atuoantibody profile in bullous pemphigoid patients.Br J Dermatol,2004,151(5):1004-1010.

共引文献5

同被引文献25

  • 1谭雪晶,涂彩霞,程艳杰,林熙然.白癜风患者血清及负压吸引疱疱液一氧化氮及相关细胞因子检测[J].中华皮肤科杂志,2003,36(7):400-402. 被引量：8
  • 2Rezaei N, Gavalas NG, Weetman AP, et al. Autoimmunity as an aetiological factor in vitiligo. J Eur Acad Dermatol Venereol, 2007, 21(7): 865-876.
  • 3Shimizu T. Role of macrophage migration inhibitory factor (MIF) in the skin. J Dermatol Sei, 2005, 37(2): 65-73.
  • 4Hamzavi I, Jain H, McLean D, et al. Parametric modeling of narrowband UV-B phototherapy for vitiligo using a novel quan- titative tool: the Vitiligo Area Scoring Index. Arch Dermatol, 2004, 140(6): 677-683.
  • 5Le Poole IC, van den Wijngaard RM, Westerhof W, et al. Presence of T cells and macrophages in inflammatory vitiligo skin paral- lels melanocyte disappearance. Am J Pathol, 1996, 148 (4): 1219-1228.
  • 6Baugh JA, Bucala R. Macrophage migration inhibitory factor. Crit Care Med, 2002, 30( 1 Suppl): S27-S35.
  • 7Moretti S, Fabbri P, Baroni G, et al. Keratinocyte dysfunction in vitiligo epidermis: cytokine microenvironment and correlation to keratinocyte apoptosis. Histol Histopathol, 2009, 24 (7): 849- 857.
  • 8Kirnbauer R, Charvat B, Schauer E, et al. Modulation of inter-cellular adhesion molecule-1 expression on human melanocytes and melanoma cells: evidence for a regulatory role of IL-6, IL-7, TNF beta, and UVB light. J Invest Dermatol, 1992, 98(3):320- 326.
  • 9Yu HS, Chang KL, Yu CL, et al. Alterations in IL-6, IL-8, GM-CSF, TNF-alpha, and IFN-gamma release by peripheral mononuclear cells in patients with active vitiligo. J Invest Der- matol, 1997, 108(4): 527-529.
  • 10Bucala R, Lolis E. Macrophage migration inhibitory factor: a critical component of autoimmune inflammatory diseases. Drug News Perspect, 2005, 18(7): 417-426.

引证文献2

二级引证文献2

中华皮肤科杂志
2010年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部