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斑马鱼神经胶质瘤模型研究进展(英文) 被引量:1

Advancements on the zebrafish glioma model
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摘要 Glioma derived from the neural ectoderm is the most common brain tumor and is of great damage to human health among all lethal tumors.Scientists have been trying their best to find new methods and develop new drugs to treat glioma in recent years.The animal glioma model is of great importance to the research.Researchers have developed many animal glioma models,like the rat and mouse model.Now we are trying to develop a new zebrafish glioma model,which has much more advantages and fewer disadvantages than the traditional models in regard to gene mutation,chemical induction,and xenografts.Establishing a glioma model in zebrafish is feasible and would be of great use to patients with this common brain tumor. Glioma derived from the neural ectoderm is the most common brain tumor and is of great damage to human health among all lethal tumors. Scientists have been trying their best to find new methods and develop new drugs to treat glioma in recent years. The animal glioma model is of great importance to the research. Researchers have developed many animal glioma models, like the rat and mouse model. Now we are trying to develop a new zebrafish glioma model, which has much more advantages and fewer disadvantages than the traditional models in regard to gene mutation, chemical induction, and xenografts. Establishing a glioma model in zebrafish is feasible and would be of great use to patients with this common brain tumor.
出处 《Chinese Journal of Cancer》 SCIE CAS CSCD 北大核心 2010年第6期621-625,共5页
基金 National Natural Science Foundation of China (No. 30672411)
关键词 神经外胚层 神经胶质瘤 临床分析 治疗方法 Zebrafish, glioma, model
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