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Chiral N-formyl amino alcohol as Lewis basic organocatalyst for enantioselective hydrosilylation of ketimines 被引量:1

Chiral N-formyl amino alcohol as Lewis basic organocatalyst for enantioselective hydrosilylation of ketimines
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摘要 Easily accessible (1R,2S)-1,2-diphenyl-2-formamidoethanol has been developed as an effective Lewis base catalyst in the enantioselective hydrosilylation of ketimines, affording high isolated yields (up to 94%) and moderate to high enantioselectivities (up to 82% ee) for a broad range of ketimines. Easily accessible (1R,2S)-1,2-dipbenyl-2-formamidoethanol has been developed as an effective'Lewis base catalyst in the enantioselective hydrosilylation of ketirnines, affording high isolated yields (up to 94%) and moderate to high enantioselectivities (up to 82% ee) for a broad range of ketimines.
出处 《Chinese Science Bulletin》 SCIE EI CAS 2010年第17期1726-1728,共3页
基金 supported by the National Natural Science Foundation of China (20672107 and 20732006)
关键词 对映选择性加成 氨基乙醇 刘易斯 手性 交通便利 发达国家 产量高 催化剂 N-formyl amino alcohol, Lewis base, organocatalyst, imine, asymmetric reduction
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