软骨母细胞瘤的MRI表现特征及其病理基础

The Correlation between MRI Manifestations and Pathologic Findings of Chondroblastoma

目的探讨软骨母细胞瘤(chondroblastoma,CB)的MRI表现特点及其病理基础。资料与方法分析经手术病理证实的13例CB的MRI表现特征,并与病理切片进行对照研究。结果全部病例在T1WI、T2WI上呈混杂信号。7例病灶边缘在T1WI及T2WI上均可见低信号环。9例有病灶邻近软组织肿胀和(或)关节囊肿胀。8例病灶周围骨髓腔内见水肿带。12例增强扫描均有不均匀明显强化。病理镜下主要由软骨母细胞和大小不等的多核巨细胞组成;7例肿瘤细胞间可见致密粗颗粒状钙盐沉积。6例可见含有暗红色液体囊腔,以及含铁血黄素沉着和组织凝固坏死。结论 CB的MRI表现较具特征性,MRI能反映其病理特性,是诊断CB的重要影像学方法 。

Objective To evaluate the correlation between MRI manifestations and pathologic findings of chondroblastoma（CB）.Materials and Methods The MRI features and the pathologic findings of 13 patients with chondroblastoma confirmed with operation were reviewed retrospectively.Results All cases demonstrated heterogeneous MR signal intensity on T1WI and T2WI images.The ring of hypointensity around the lesion on T1WI and T2WI images was seen in 7 cases.Adjacent joint effusion and a soft tissue swelling were visible in 9 cases.Surrounding bone marrow edema was found in 8 cases.Heterogeneous enhancement was seen in 12 cases.Histopathologically,the tumors were composed of chondroblast and multinucleated giant cell.There were cartilaginoid stroma and calcification as lattice appeared inter the chondroblasts in 7 cases.Six cases showed blood filled spaces with hemosiderosis and necrotic tissue.The MRI features were closely correlated with the pathological findings.Conclusion MRI presentation is an important technique in diagnosis of chondroblastoma,which can reflect the pathologic changes of chondroblastoma.