摘要
肠易激综合征是常见的功能性肠病,其发病机制不但涉及肥大细胞、肠嗜铬细胞的数量异常,5-羟色胺等细胞因子、细胞通透性也发生改变,还涉及免疫系统等的异常。
Irritable bowel syndrome is one of the most common functional gastrointestinal disorders(FGIDs).Abnormal of cell(mast cell and enteroendocrine cell)number,changes of cytokine(5-HT,et al)and cell permeability may be involved in the patho-genesis of irritable bowel syndrome(IBS).Immune activation also plays a pathogenic role in IBS.
出处
《胃肠病学和肝病学杂志》
CAS
2010年第6期577-580,共4页
Chinese Journal of Gastroenterology and Hepatology
基金
国家自然科学基金资助项目(No.30570822)
关键词
肠易激综合征
肥大细胞
肠嗜铬细胞
免疫
Irritable bowel syndrome
Mast cell
Enteroendocrine cell
Immune