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高血压个体化药物治疗相关基因分型芯片数据分析软件设计 被引量：1

Software design for data analysis of individual antihypertensive drugs therapy related genotyping microarray
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摘要 目的:针对高血压个体化药物治疗相关基因分型芯片,设计高血压芯片数据分析v1.0软件。通过读取芯片扫描后产生的GPR或LSR文件,自动分析芯片工艺的有效性、判断相关的基因型结果并入库管理。方法:以Microsoft VisualBasic V6.0为工具编程。结果:经过1025例芯片的测试结果表明,该软件稳定可靠,大大提高了基因分型工作效率。结论:软件设计成功,达到预期目的。 AIM：Base on individual antihypertensive drugs therapy related genotyping microarray, with platform of Microsoft Visual Basic 6.0,developed hypertension microarray data analysis system vl.0.By reading GPR or LSR file produced by microarray scanners,the system automatic determine microarray validity,generate relative genetype result and store for later database manage.METHODS：The Microsoft Visual Basic V6.0 was used for programming tools.RESULTS.After analysised 1025 microarray, the results showed that system run smoothly and reliable,greatly increased the analysis efficiency. CONCLUSION：Software design succeed, achieved the desired objectives.
作者 黄远飞 彭健 赵震宇 杨洪 肖鹏 唐静波 沈杰 张阳德
机构地区 中南大学卫生部肝胆肠外科研究中心 中南大学临床药理研究所 中南大学湘雅医院肝胆肠外科研究中心 安徽省药物临床评价中心
出处 《中国临床药理学与治疗学》 CAS CSCD 2010年第4期438-442,共5页 Chinese Journal of Clinical Pharmacology and Therapeutics
基金 安徽省教育厅(2009SQRZ181)
关键词 高血压 微点阵 基因芯片 VB6.0个体化药物治疗 单核苷酸多态性 Hypertension Microarray Gene chip Visual basic v6.0 Individual medication SNP
分类号 R969 [医药卫生—药理学]
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中国临床药理学与治疗学
2010年 第4期

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