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真核细胞翻译起始因子eIF4E与白血病

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摘要 真核细胞翻译起始因子eIF4E在30%以上的人类恶性肿瘤中过表达,靶向eIF4E及其上游通路的药物可以部分抑制肿瘤细胞的生物学行为。本文就eIF4E在白血病中的作用及其靶向治疗的研究进展作一综述。
出处 《国际输血及血液学杂志》 CAS 2010年第3期249-253,共5页 International Journal of Blood Transfusion and Hematology
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