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冠状动脉内注射维拉帕米在PCI中无复流患者中的应用 被引量：5

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摘要 目的观察冠状动脉内注射维拉帕米治疗经皮冠状动脉介入术(PCI)中无复流现象的临床疗效。方法将同期于我院行PCI且术中出现无复流的123例冠心病患者随机分为观察组58例和对照组65例,两组手术方法相同,出现无复流现象后分别经冠状动脉内注入维拉帕米和硝酸甘油。观察两组注射药物后首次和PCI中末次造影图像,评估心肌梗死溶栓试验(TIMI)血流分级、TIMI心肌组织灌注分级(TMPG);同时观察术后1周左室射血分数(LVEF)及住院期间、术后60 d内主要心血管事件(MACE)发生情况。结果观察组两次冠状动脉造影TIMI 3级血流获得率、TMPG 3级获得率均明显高于对照组,术后1周LVEF显著高于对照组,住院期间及PCI术后60 d内MACE发生率显著低于对照组,P均<0.01。结论PCI中冠状动脉内注射维拉帕米可明显改善患者血流、心功能,减少MACE发生。
作者 张红雨 曹艳君 吴志国 王立强 张霞
机构地区 天津医科大学宝坻临床学院
出处 《山东医药》 CAS 北大核心 2010年第23期54-56,共3页 Shandong Medical Journal
关键词 冠状动脉 血管成形术 经腔 经皮冠状动脉 无复流 维拉帕米
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献11

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二级参考文献46

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共引文献106

同被引文献80

引证文献5

二级引证文献23

山东医药
2010年 第23期

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