摘要
在稀H2SO4介质中，头孢唑啉钠在滴汞电极上于-0．70V（vs．SCE）处产生一灵敏的极谱还原峰，头孢唑啉钠的浓度在0．8-600μg／mL范围内与其所产生的峰电流呈线性关系，建立了用单扫描示波极谱法测定药物中头孢唑林钠含量的新方法，此方法检出限为0．41μg／mL。用于实际药品制定，结果与药典法一致。
In a supporting electrolyte containing dilute H2SO4, a reductive peak of cefazolin sodium was observed at --0. 70 V （vs. SCE）. A liner relationship was found between the intensity of the cefazolin sodium peak and the concentration of cefazolin sodium in the range of 0.8-600 μg/mL, and the detection limb was 0. 41μ g/mL. A new method for the determination of cefazolin sodium by linear-sweeping oscillopolarography was established. The results agree very well with those obtained by the conventional pharmacopoeial method.
出处
《化学世界》
CAS
CSCD
北大核心
2010年第6期324-326,共3页
Chemical World
基金
河南省教育厅自然科学基金资助项目(2008B150024)
关键词
单扫描示波极谱法
头孢唑啉钠
药物
linear-sweeping
oscillopolarography
cefazolin sodium
medication
