妊娠期高血压合并胎儿宫内生长受限91例临床研究

Pregnancy Induced Hypertension Complicated with Fetal Growth Restriction:a Report of 91 Cases

目的探讨妊娠高血压合并胎儿宫内生长受限(FGR),降低围生儿死亡,改善围生儿预后的途径。方法将2005年1月-2009年12月妊娠高血压合并FGR孕晚期未治疗终止妊娠30例为A组,治疗一周后终止妊娠61例为B组,并选同期妊高征无FGR40例为C组,比较三组孕妇的妊娠结局。结果 A组胎盘早剥、羊水粪染、电子监护异常(NST或OCT),Apgar评分低、围生儿死亡的发生率明显高于B组和C组(P<0.05),而B组胎盘早剥、羊水粪染、电子监护异常,Apgar评分低、围生儿死亡的发生率也高于C组(P<0.05)。结论加强孕期保健,尽量早期发现,早期诊断,适时治疗,可以明显改善围生儿的预后。

Objective To explore pregnancy induced hypertension complicated with fetal growth restriction （FGR）,to reduce perinatal mortality,and to improve the prognosis of perineonate.Methods Ninety-one patients with pregnancy induced hypertension and FGR from January,2005 to December,2009 were divided into group A （n=30） and group B （n=61）.The patients of group A were untreated and the pregnancies were terminated in the third trimester of gestation.The patients of group B received one-week of treatment before termination of gestation.40 pregnancy induced hypertension patients without FGR were served as group C.The pregnancy outcomes of the three groups were compared.Results The incidence rates of placental abruption,amniotic fluid turbidity,NST or OCT abnormality,the lower score of Apgar and the mortality of perineonates of group A were significantly higher than those of groups B and C （P〈0.05）.And all the above indexes of group B were higher than those of group C （P〈0.05）.Conclusions Enhancement of health care for pregnant women,early discovery and diagnosis,and timely treatment can significantly improve the prognosis of the perineonate.