重庆市5782例体检人群代谢综合征与脂肪肝的相关性研究

Association research between metabolism syndrome and fatty liver of 5782 health examination cohort in Chongqing

目的:研究重庆市5782例体检人群代谢综合征(Metabolism syndrome,MS)与脂肪肝的患病率,以探讨二者的相互关系。方法:将研究对象按年龄、性别分组,分析5782例体检人群代谢综合征与脂肪肝的患病率,比较不同年龄段和性别间MS和脂肪肝患病率的差异。采用logistic回归分析对脂肪肝与年龄、性别、BMI、GLU、TC、TG、HDL-C、LDL的关系进行相关性分析,比较脂肪肝组和非脂肪肝组肥胖、HBP、高血糖和血脂紊乱发生率的优势比(Odds ratio,OR)。结果:5782例体检人群中MS、脂肪肝的患病率分别为9.58%、25.9%;代谢综合征的患病率随年龄增加而增加,男性代谢综合征和脂肪肝的患病率明显高于女性(P<0.001);Logistic回归分析表明对脂肪肝患病率有影响的是性别、BMI、GLU、TC、TG、HDL-C6项;与非脂肪肝组相比,脂肪肝组肥胖、HBP、高血糖和血脂紊乱患病率显著增加,脂肪肝组肥胖、HBP和血脂紊乱患病率的OR分别为9.03、3.08、4.11和5.09。结论:重庆市脑力劳动人群MS与脂肪肝的患病率较高,MS与脂肪肝有很密切的关系,及早进行健康体检并做B超筛查,改变不良生活习惯有利于对二者的早期防治。

Objective：To study the incidence rates of metabolism syndrome（MS）and fattyliver of 5782 health examination cohort in Chongqing to further investigate the interrelation of the two diseases.Methods：Subjects were divided into different groups according to age and gender,the incidence rates of MS and fatty liver of 5782 health examination cohort were analyzed and the incidence rate variances of MS and fatty liver between different age and gender groups were compared.Logistic regression analysis was used to analyze the dependability between fatty liver and age,gender,BMI,GLU,TC,TG,HDL-C and LDL.The incidence odds ratio（OR）of obesity,high blood pressure（HBP）,high blood glucose and blood lipids disorder between fatty liver group and non-fatty liver group were compared.Results：Among the 5 782 participants,the incidence rates of MS and fatty liver were 9.58% and 25.9% respectively.The incidence rate of MS increased as age increases,and the incidence rates of MS and fatty liver in male were obviously higher than those in female（P0.001）;Logistic regression analysis showed the incidence rate of fatty liver was influenced by six factors including gender,BMI,GLU,TC,TG and HDL-C;Compared with non-fatty liver group,the incidence OR of obesity,HBP and blood lipids disorder in fatty liver group significantly increased and were 9.03,3.08,4.11 and 5.09 respectively.Conclusion：The incidence rates of MS and fatty liver are high in mental labor cohort of Chongqing,and MS and fatty liver have close relationship.To have health examination and B type ultrasound screening and change bad living habits as soon as possible are beneficial for the early prevention and management of the two diseases.