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昆虫嗅觉相关蛋白的结构和功能 被引量:8

Structure and Function of Insect Olfactory Proteins
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摘要 昆虫在长期进化的过程中形成了复杂的嗅觉系统,气味剂结合蛋白(odorant binding proteins,OBPs)、嗅觉受体(olfactory receptors,ORs)是其最主要的组分.其主要作用是结合外围挥发性的气味分子并将信号传递给细胞内的第二信使.OBPs和ORs的结构、功能、表达、进化是昆虫行为与进化关系的重要研究领域和研究热点.本文主要总结了近年来昆虫OBPs和ORs的结构特点、生理功能、表达特点、遗传进化等方面研究的最新进展,对OBPs和ORs的研究趋势进行了展望,为昆虫嗅觉系统进化研究及寻找害虫防治新途径提供参考信息. Insects have developed complicated olfaction systems during the long evolution progress.As the important components of insect olfaction systems,odorant binding proteins (OBPs) and olfactory receptors (ORs) mainly combine with the volatility signal molecule in the periphery and transfer the signal to the second messenger.The structure,function,expression and evolution of OBPs and ORs are important to study the relationship between insect behavior and evolution.This paper summarizes the lately research progress of OBPs and ORs,including the characteristics of structure,physiological function,gene expression,genetics and evolution.The current of OBPs and ORs research was also discussed in this paper,which may provide reference for the research of olfaction systems and finding new approaches of defending pests.
出处 《中国生物化学与分子生物学报》 CAS CSCD 北大核心 2010年第6期531-537,共7页 Chinese Journal of Biochemistry and Molecular Biology
基金 国家自然科学基金(No.30871660) 教育部高等学校博士学科点专项科研基金(No.20094404110019)项目资助~~
关键词 气味剂结合蛋白 嗅觉受体 结构 功能 进化 odorant binding proteins olfactory receptor structure function evolution
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