镰形棘豆霜制备工艺的优化研究

Optimization study on preparation technology of falcate crazyweed herb cream

目的探讨O/W型镰形棘豆霜的最佳制备工艺与处方。方法采用正交实验设计法,通过考察乳化条件对乳膏质量、稳定性的影响和有效成分添加量对紫外吸收性能的影响,确定最佳的制备工艺与处方。结果乳化剂司盘-60与吐温-80比例为20:35,分别加入油相和水相,乳化温度为80℃时,所得基质稳定,均匀细腻,易于涂抹;镰形棘豆总黄酮提取物加入量为2.5%时,所制霜剂具有良好的稳定性和较好的紫外吸收效果。结论产品的稳定性及紫外吸收性能良好,有望进一步开发成一种新型的天然防晒用品。

Objective To optimize the formulation and preparation process of falcate crazyweed herb cream of O/W type.Methods The orthogonal experimental design is applied.By investigating the emulsification conditions impacting the quality and stability of the cream as well as the adding amount of active ingredient impacting the UV absorption property,the optimum preparation process and the best prescription are determined.Results When the ratio of emulsifier span-60Tween-80 was 2035,the oil phase and water phase are added respectively.When the emulsifying temperature was 80 ℃,the emulsion can gain stable quality and uniformity texture.When the adding amount of the total flavones reaches 2.5%（w）,the obtained cream has a good stability and good UV absorption.Conclusion Both stability and UV absorption property of the product are satisfactory,which is expected to be developed further into a new kind of natural sunscreen articles.