四川省凉山彝族地区囊尾蚴病血清学调查(英文)

Seroprevalence of Cysticercosis in Ethnic Yi Community of Sichuan Province,China

目的了解四川省凉山州彝族地区囊尾蚴病感染情况和流行风险因素。方法于2006年对凉山州昭觉县比尔乡的部分居民问卷调查;猪带绦虫尾蚴GPs作为抗原,用ELISA方法检测人、猪血清猪囊尾蚴特异性抗体。结果当地居民继发型癫痫发作率为9.1%(57/626),人、猪血清阳性率分别为7.2%(36/499)、13.9%(14/101)。该病在当地流行的主要原因包括猪放养、不良食肉习惯(坨坨肉)、人无厕所、肉品检疫不严以及经济落后等。结论囊尾蚴病高度流行于四川省彝族地区。为控制该病的流行,必需采取综合性的防治措施,如主动的人群绦虫病筛查和治疗、加强肉食品检疫和人粪管理、改变不良饮食习惯、提倡猪圈养等。

Objective To understand the infection rate of cysticercosis in humans and pigs,and analyze the risk factors for the transmission of Taenia solium in ethnic Yi communities of Liangshan Prefecture,Sichuan province.Methods This village-based study was conducted in 2006 in Bier ethnic Yi Township of Zhaojue county,Lianshan prefecture.Questionnaire survey was performed among the local residents,and serum samples from the local residents and pigs were detected for specific IgG antibody against Taenia solium cyst GPs antigen by ELISA.Results A total of 9.1%（57/626）of local residents reported symptoms indicating the history of probable late-onset epilepsy,and 7.2%（36/499）of local people and 13.9%（14/101）of local pigs were positive for cysticercosis specific antibody.The factors including the free-range pig raising,prevalence of consumption of undercooked pork,lack of household latrine facilities,inadequate meat inspection and poor economy were considered to contribute to the severe transmission of T.solium taeniasis/cysticercosis in this ethnic Yi community.Conclusion Cysticercosis is highly endemic in this ethnic Yi community of Sichuan province.Integrated intervention measures,such as active mass screening and further treatment of taeniasis carriers,enhancement of meat inspection,proper disposal of human faeces,changing pork consumption habits and pig raising practices,are imperative to be performed in this highly endemic area to control this neglected disease.