基因兴奋剂检测方法及检测技术应用述评

Review of the application of gene stimulant test methods and technologies

随着基因治疗技术的成功应用和不断完善,基因兴奋剂将成为体育界和世界反兴奋剂机构(WADA)面临的新威胁。因此,开发切实可行的基因兴奋剂检测方法是各国科学家所共同努力的目标。在总结前人成果的基础上,从基因、蛋白质、载体和免疫反应方面对基因兴奋剂的检测进行综述,并展望新技术在检测中的应用。

With the successful application and constant perfection of gene therapy technologies,gene stimulants will become new threats to the sports community and the World Anti-Doping Agency（WADA）.Therefore,developing practically feasible gene stimulant test methods is the goal to be achieved jointly by scientists in countries all over the world.On the basis of summarizing achievements made by predecessors,the authors gave an overview of the testing of gene stimulants in terms of genes,proteins,carriers and immune reactions,and expected the application of new technologies in the testing.