3Blank N, Schiller M, Krienke S, et al. Atorvastatin inhibits T cell activation through 3-Hydroxy-3-methylglutaryl coenzyme A reductase without decreasing cholesterol synthesis [J]. J Immunology, 2007,179 (6) :3613-3621.
4Wibaut Berlaimont V, Randi AM, Mandryko V, et al. Atorvastatin affects leukocyte gene expression in dyslipidemia patients: in vivo regulation of hemostasis, inflammation and apoptosis[J]. J thromb Haemost, 2005,3(4) : 677-685.
3Wang H R,Li J J,Huang C X,et al.Fluvastatin inhibits the expression of tumor necrosis factor-alpha and activation of nuclear factor-kappaB in human endothelial cells stimulated by C-reactive protein[J].Clin Chim Acta,2005,353(1-2):53-60.
4Ridker P M,Hennekens C H,Buring J E,et al.C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women[J].N Engl J Med,2000,342(12):836-843.
5Ridker P M,Rifai N,Pfeffer M A,et al.Inflammation,pravastatin,and the risk of coronary events after myocardial infarction in patients with average cholesterol levels.Cholesterol and Recurrent Events (CARE) Investigators[J].Circulation,1998,98(9):839-844.
6Morrow D A,Rifai N,Antman E M,et al.C-reactive protein is a potent predictor of mortality independently of and in combination with troponin T in acute coronary syndromes:a TIMI 11A substudy.Thrombolysis in Myocardial Infarction[J].J Am Coll Cardiol,1998,3(7)1:1460-1465.
7Zhou T,Zhou S H,Qi S S,et al.The effect of atorvastatin on serum myeloperoxidase and CRP levels in patients with acute coronary syndrome[J].Clin Chim Acta,2006,368(1-2):168-172.
1Mendel I,Yacov N, Harats D, et al. Therapies targeting innate im-munity for fighting inflammation in atherosclerosis [ J]. Curr PharmDes,2015, 21(9) : 1 185-195.
2Chen GY, Nunez G. Sterile inflammation: sensing and reacting todamage[ J]. Nat Rev Immunol, 2010,10(12) : 826-837.
3Martinon F, Bums K, Tschopp J. The inflammasome: a molecularplatform triggering activation of inflammatory caspases and processingof proIL-beta[ J]. Mol Cell, 2002, 10(2) : 417-426.
4Lu XJ, Kakkar Y. Inflammasome and atherogenesis[ J]. Curr PharmDes, 2014, 20(1) : 108-124.
5Im SS, Yousef L, Blaschitz C, et al. Linking lipid metabolism to theinnate immune response in macrophages through sterol regulatory el-ement binding protein-la[ J]. Cell Metab, 2011,13(5) : 540-549.
6Arazi SS, Genvigir FD, Willrich MA, et al. Atorvastatin effects onSREBFla and SCAP gene expression in mononuclear cells and itsrelation with lowering-lipids response [ J ], Clin Chim Acta,2008,393(2) : 119-124.
7Chen P, Xia K, Zhao Z, et al. Atorvastatin modulates theDDAH1/ADMA system in high-fat diet-induced insulin-resistantrats with endothelial dysfunction [ J ]. Vase Med, 2012,17(6):416-423.
8Bhaskar V, Yin J, Mirza AM, et al. Monoclonal antibodiestargeting IL-1 beta reduce biomarkers of atherosclerosis in vitroand inhibit atherosclerotic plaque formation in apolipoprotein E-deficient mice[ J]. Atherosclerosis, 2011,216(2) : 313-320.
10Wang Y, Chang H, Zou J, et al. The effect of atorvastatin on mR-NA levels of inflammatory genes expression in human peripheralblood lymphocytes by DNA microarray [J]. Biomed Pharmacother,2011,65(2) : 118-122.