不同氧流量对老年慢性阻塞性肺疾病患者心率及动脉血氧饱和度的影响

Effects of Different Oxygen Flow Rate on Heart Rate and Arterial Oxygen Saturation in Elderly Patients with Chronic Obstructive Pulmonary Disease

目的评估氧气雾化吸入疗法中不同氧流量对老年慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者雾化吸入前后心率及动脉血氧饱和度变化的影响。方法对32例采取氧气雾化吸入疗法的COPD患者,分别选择氧流量为4、5、6、7、8L/min,观察患者雾化吸入前后心率及动脉血氧饱和度变化的情况,并进行统计学处理。结果氧流量为4～6L/min时,雾化前后患者心率变化较小,差异无统计学意义。氧流量为7～8L/min时,雾化前后患者的心率变化较大,差异有统计学意义(P<0.05)。但是无论氧流量大小,雾化后患者的动脉血氧饱和度均增加,与雾化前相比差异有统计学意义(P<0.05)。结论在COPD患者进行氧气雾化疗法时,为达到最佳的雾化效果,建议采用氧流量在5～6L/min。

Objective To evaluate the effect of the different oxygen flow rate of the fog inhalation therapy on the heart rate and arterial oxygen saturation in the elderly patients with chronic obstructive pulmonary disease（COPD）.Method Thirty-two COPD patients were treated by aerosol inhalation of oxygen by the oxygen flow rates of 4,5,6,7,8 L/min separately.The changes of heart rate and arterial oxygen saturation of the patients were observed and analyzed statistically.Results Before and after the therapy,the change of heart rate was minimal and not statistically significant at the oxygen flow rate of 4-6 L/min.While the heart rate was maximal and statistically significant at the oxygen flow rate of 7-8 L/min（P0.05）.The arterial oxygen saturation after the fog inhalation therapy was increased at whatever the oxygen flow rate was,and there were significantly differences（P0.05）.Conclusion It is suggested to adopt the oxygen flow rate of 5-6 L/min when the fog inhalation therapy is used in the clinical practice.