心房颤动患者的危险因素分析

Clinical analysis of related risk factors in patients with atrial fibrillation

目的探讨心房颤动(房颤)患者的相关危险因素,旨在防止房颤的发生。方法对我院2006年5月至2008年12月,643例房颤患者的住院资料进行回顾性分析,并按年龄分组,分析老年人房颤的特点。结果 643例房颤患者,年龄40～94岁,男女比例为1∶0.68;房颤病因中,<50岁患者最常见的是孤立性房颤,≥60岁患者的常见病因为高血压。非瓣膜性房颤患者中,阵发性房颤患者左心房直径显著小于持续性房颤和永久性房颤患者(P<0.01),左心室射血分数显著高于持续性房颤和永久性房颤患者(P<0.01)。阵发性房颤患者中心功能Ⅱ～Ⅳ级所占比例较持续性房颤和永久性房颤患者明显减少(P<0.01)。结论房颤的发生随年龄增加而明显增加;高血压、冠心病、糖尿病、风湿性心脏病、心功能不全、心衰等均是房颤的危险因素。

Objective To analyze the related risk factors of the atrial fibrillation （AF）. Methods The clinical data of 643 AF in-patient cases in our hospital in 3 years （from 2006 to 2008） were selected and analyzed retrospectively. All the AF cases were divided into different groups by age,and the characters of AF in the elderly were analyzed. Results The enrolled patients aged 40-94 years,male to female ratio was 1：0.68. The primary pathogenic cause of AF was lone AF in the group less than 50 years old.The primary pathogenic cause of AF was hypertension in the group of patients 60 years and older. In non-valvular AF patients,the left atrium diameter was smaller and the left ventricular ejection was higher in paroxysmal AF patients than those in persistent AF and permanent AF patients （P〈0.01）. The ratio of cardiac function Ⅱ-Ⅳ in paroxysmal AF was smaller than that in persistent AF and permanent AF patients（P〈0.01）. Conclusions The incidence of AF increases with age,and hypertension,rheumatic heart disease,coronary heart disease,diabetes,cardiac dysfunction are all risk factors of AF.