摘要
测定急性冠脉综合征(ACS)患者血清中氨基末端B型钠尿肽前体(NT-proBNP)和超敏CRP(hs-CRP)水平,探讨其临床意义。应用强生Vitros ECi免疫发光仪对血清NT-proBNP的含量进行测定,应用放射免疫分析法检测患者血清中hs-CRP的水平。结果显示,与对照组相比,患者血清中NT-proBNP和hs-CRP水平显著升高,差异有统计学意义(P<0.05),联合检测NT-proBNP和hs-CRP,对ACS诊断的特异性可达100%。结论:血清中NT-proBNP和hs-CRP的联合测定对ACS的分析判断有重要意义。
To explore the clinical significance the serum levels of N-Terminal proB-Type natriuretic peptide（NT-proBNP） and high-sensitivity C-reactive protein（hs-CRP） in patients with acute coronary syndrome,the serum levels of NT-proBNP and hs-CRP in patients and normal controls were determined by ECi Immunity Analyzer and radioimmunoassay respectively.The results showed that the serum levels of NT-proBNP and hs-CRP in patients with acute coronary syndrome were significantly higher than that of controls（P0.05）.The diagnostic specificity for acute coronary syndrome was 100% by combined detection of NT-proBNP and hs-CRP.The results suggest that the combined detection of serum NT-proBNP and hs-CRP levels are very important to evaluate heart function in patients with acute coronary syndrome.
出处
《标记免疫分析与临床》
CAS
2010年第3期143-145,共3页
Labeled Immunoassays and Clinical Medicine
关键词
急性冠脉综合征
氨基末端钠尿肽前体
超敏CRP
Acute coronary syndrome
N-Terminal proB-type natriuretic peptide
High sensitive C-reactive protein
