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SDF-1/CXCR4在造血干细胞动员相关研究新进展 被引量：1

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作者 吕亮亮 李桥川 赖永榕
机构地区 广西医科大学第一附属医院血液科
出处 《蛇志》 2010年第2期130-132,共3页 Journal of Snake
基金 广西自然科学基金(NO:0728124) 广西医科大学2008年研究生创新计划项目(NO:2008105891002M205)
关键词 造血干细胞 基质细胞衍生因子 基质细胞衍生因子受体 基质细胞衍生因子拮抗剂
分类号 R977.8 [医药卫生—药品]
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参考文献10

  • 1Pease J E, Horuk R. Chemokine receptor antagonists: Part 1 [J]. Expert Opin Ther Pat, 2009,19(2), 39-85.
  • 2Ma Q,Jones D,Springer T A. The chemokine receptor CXCR4 isrequired for the retention of B lineage and granulocytic pre- eursorswithin the bone marrow microenvironment[J]. Immunity, 1999,10(4) : 463-471.
  • 3Bonig H, Priestley G V,Oehler V, et al. Hematopoietie progenitor cells (HPC) from mobilized peripheralblood display enhanced migration and marrow homingeompared to steady-state bone marrow HPC[J]. Exp Hematol, 2007,35 (2): 326-334.
  • 4Jin F,Zhai Q,Qiu L,et al. Degradation of BM SDF-1by MMP- 9:the role in G-CSF-induce hematopoietic stem/progenitor cell mobilization [J]. Bone Marrow Transplant, 2008,42 (9): 581- 588.
  • 5Petit I,Szyper-Kravitz M, Nagler A, et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and upregulating CXCR4[J]. Nature Immunology,2002,3(7):687-694.
  • 6Lee H M, Wu W, Wysoczynski M, et al. Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes[J]. Leukemia, 2009,23 (11), 2052-2062.
  • 7Reea R, Mastellos D, Majka M, et al. Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/ progenitor cells, and C3a enhances their homing-relatedresponses to SDF-1 [J]. Blood, 2003, 101(10):3784-3793.
  • 8Jalili A, Shirvaikar N, Marquez-Curtis L, et al. Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis,further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells [J]. Exp Hematol,2010,38(4) :321-332.
  • 9Calandra G, McCarty J, MeGuirk J, et al. AMD3100 plus G-CSF can successfully mobilize CD34A- cells fromnon-Hodgkin's lymphoma,Hodgkin's disease and multiple myelomapatients previously failing mobilization with chemotherapy and/orcytokine treatment:compassionate use data[J]. Bone Marrow Transpl, 2008,41(4) :331-338.
  • 10Devine S M, Vij R, Rettig M, et al. Rapid mobilization of functional donor hematopoietic cells withoutG-CSF using AMD3100, an antagonist of the CXCR4/SDF-linteraction[J]. Blood, 2008,112 (4): 990-998.

同被引文献21

  • 1黎金凤,霍亚南.基质细胞衍生因子-1对外周血内皮祖细胞功能影响的研究进展[J].江西医药,2013,48(4):369-371. 被引量：5
  • 2Bhakta S, Hong P, Koe O. The surface adhesion molecule CXCR4 stimulates mesenchymal stem cell migration to stromal cell-derived factor-1 in vitro but does not decrease apoptosis under serum depri- vation[J]. Cardiovasc Revasc Med, 2006, 7(1): 19-24.
  • 3Li Q, Zhang A, Tao C, et al. The role of SDF-1-CXCR4/CXCR7 axis in biological behaviors of adipose tissue-derived mesenchymal stem cells in vitro[J]. Biochem Biophys Res Commum, 201a, 441 (3) : 675-680.
  • 4Gebura K, Bogunia-Kubik K. Clinical relevance of chemokine recep- tor CXCR4[J]. Postepy Hig Med Dosw(Online), 2012, 66: 252- 266.
  • 5Bobadilla M, Sainz N, Abizanda G, et al. The CXCR4/SDF1 axis improves muscle regeneration through MMP-10 activity[J]. Stem Cells Dev, 2014, 23(12): 1417-1427.
  • 6Van Weel V, Seghers L, de Vries MR, et al. Expression of vascular endothelial growth factor, stromal cell-derived factor-i, and CX- CR4 in human limb muscle with acute and chronic ischemia[J]. Ar- terioscler Thromb Vasc Biol, 2007, 27(6): 1426-1432.
  • 7Takahashi M. Role of the SDF-1/CXCR4 system in myo-eardial in- faretion[J]. Circ J, 2010, 74(3): 418-423.
  • 8Dimova I, Hlushchuk R, Makanya A, et al. Inhibition of Notch sig- naling induces extensive intussusceptive neo-angiogenesis by recruit- ment of mononuclear cells[J]. Angiogenesis, 2013, 16 (4): 921- 937.
  • 9徐其渊.CXCR4表达在衰老骨髓细胞中的变化及其对血管再生功能的影响[D].浙江大学学报(理学版),2010.
  • 10Haraguchi T, Tani K, Koga M, et al. Matrix Metalloproteinasess (MMPs)Aetivity in Cu-ltured Canine Bone Marrow Stromal Cells (BMSCs)[J]. J Vet Med Sci, 2012, 74(5): 633-636.

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蛇志
2010年 第2期

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