广州市某三甲医院3000例门诊患者抗生素使用情况调查

Outpatient Utilization of Antibiotics a 3-A Hospital in Guangzhou:Analysis of 3000 Cases

目的:了解广州市某三甲医院抗生素应用情况,为临床合理用药提供参考。方法:随机抽取广州市某三甲医院2009年3000张门诊病例处方,以DDDs为指标,对抗生素种类、金额、剂型等进行统计分析。结果:调查的3000张处方中,抗生素使用率为31.56%,且以头孢菌素类、青霉素类和氟喹诺酮类应用最为广泛,抗生素药物金额占总金额的36.98%,用药以单用为主,联合用药以二联为主,三联少见、暂未见四联用药,少数复方制剂也有应用,应用剂型主要为口服制剂。结论:该院抗生素使用基本合理,但还存在一些不足之处,故必须彻底贯彻安全、有效、经济、合理的用药原则,杜绝抗生素的滥用。

OBJECTIVE：To review the utilization of antibiotics in a 3-A hospital in Guangzhou for reference for clinical rational medication.METHODS：A total of 3 000 outpatient prescriptions randomly collected from a 3-A hospital in Guangzhou were analyzed statistically with regard to drug variety,consumption sum and dosage forms by taking DDDs as indicators.RESULTS：Of the 3 000 prescriptions reviewed,antibiotic use occupied 31.56% and the most widely used categories were cephalosporins,penicillins,and fluoroquinolones.The consumption sum of antibiotics occupied 36.98% of total,with one-kind antibiotic prescriptions showing the highest proportion.Of the drug combination schemes,combination of two drugs showed the highest proportion,while the combination of 3 antibiotics were few,and combination of 4 antibiotics has not been noted.Application of a few compound preparations was noted.Oral dosage forms took a lead.CONCLUSION：The use of antibiotics in this hospital is generally rational yet far from perfect,thus we must adhere to the principle of safe,effective,economic and rational drug use and eliminate the abuse of antibiotics.