摘要
采用斑点杂交(Dotblot)对10例人原发性肝癌和癌周肝组织中的HSU17714基因的mRNA表达进行了比较研究。结果表明,HSU17714基因在肝癌组织和癌周肝组织中的表达有极显著差异(P<0.01)。10例样品中,7例肝癌组织中HSU17714mRNA表达显著高于癌周肝组织,2例在两种组织中的表达无差异,1例在癌周组织中HSU17714mRNA表达略高于肝癌组织。该实验结果表明HSU17714基因表达与肝癌有显著相关性。
Comparative studies on mRNA expression of HSU 17714 gene in primary hepatic cancers (PHC) and the adjacent liver tissues of 10 patients were performed by using Dot blot hybridization The results showed that distinct expression of HSU 17714 gene was found in PHC and its adjacent liver tissues ( P <0 01) Among the 10 cases, 7 cases showed a much higher mRNA expression of HSU 17714 gene in PHC than in the adjacent liver tissues, 2 had no difference in both kinds of tissues and 1 slightly higher mRNA expression of HSU 17714 gene in liver tissue than in PHC These results indicated that there was an obvious relationship between up regulated expression of HSU 17714 gene and PHC
出处
《同济医科大学学报》
CSCD
1999年第1期45-46,共2页
Acta Universitatis Medicinae Tongji