3Nemuaitis J, Swisher SG,Timmons T, et al.Adenovirus-mediated p53 gene transfer in sequence with cisplatin totumors of patients with non-small-cell lung cancer [J]. J Clin Oncol, 2000, 18:609-622
4Schuler M, Herrmann R, De Greve JL, et al.Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-smallcell lung cancer: results of a mulficenter phase Ⅱ study [J]. J Clin Oncol, 2001, 19:1750-1758
5Hunt KK, Vorburger SA. Hurdles and hopes for cancer treat ment[J] . Science, 2002,19: 415.
6Yumi knegae. Miho makimura and Izumu satio. Asimple and efficient method for purfica - tion of infections recombinant adenovirus[J] . Jpn J Med Sci BioI, 1994,47:157.
7Frank DK,Frederick MJ,Liu TJ, et al. Bystander effect in the adenovirus - mediated wild - type p53 gene therapy model of human squamous cell carcinoma of the head and neck[J ]. Clin Cancer Res, 1998,4:2 521.
8Vorburger SA,Hunt KK. Adenoviral gene therapy[J].Oncologist, 2002,1: 46.