摘要
本文采用放射免疫方法(RIA),检测荷S180肿瘤小鼠外周血中TNF-α的含量,观察双歧杆菌(Bifidobacterium)及其细菌壁(CelWalsofBifidobacterium,B-CW)的免疫调节作用,探讨其抗肿瘤机制。结果表明该菌及其B-CW均可明显地促进机体产生TNF-α。
A strain of Oxygen-resistant Bifidobacterium and it's cell walls were used to treat the mice with S 180 Sarcoma, To investigate the role of cytokiues in interaction between Bifidobacterium or it's cell walls and the immune system, we used Radioimmunoassay (RIA) to measure prodution of TNF-α (tumor necrosis factor alpha) from serum of mice after 5 times stimulation with bacterium and it's cell walls. It was found that TNF-α was greatly induced in vivo with Bifido baceerium and it's cell walls. Our resules sugges that Bifido bacterium and it's wall can play an antitumor effect via stimulating nonspectific immunity.
出处
《中国微生态学杂志》
CAS
CSCD
1999年第1期14-15,共2页
Chinese Journal of Microecology
基金
江苏省卫生厅资助