色谱技术在中药有效成分辨识中的应用进展

Advanced development of chromatography in screening and identification of effective compounds in Chinese materia medica

中药效应成分辨识是中药质量控制研究的关键,本文从化学特性、生物靶标和整体作用三个层面综述了2000年以来色谱技术在中药效应成分辨识研究中的应用进展,并提出未来发展方向.

Screening and identification of effective compounds in Chinese materia medica is the key for its quality control,which is critical for ensuring the safety and efficacy in clinic.Herein,the advanced development of chromatography in screening and identification of effective compounds in Chinese materia medica since 2000 was reviewed based on the strategies of chemical characteristics,drug targets and integrating chemical analysis and pharmacological assay.The prospect of chromatography in this field was also discussed.