摘要
缺血/冉灌注（ischemia reperfusion,I/R）损伤可导致局部和/或远端组织器官的损伤;缺血预处理（ischemic preconditioning,IPC）是对I/R损伤的一种有效处理方式;远端预处理（remote preconditioning,RPC）是继IPC后一种新兴的,更简单又经济的,高效的保护组织器官免受缺血损伤的策略,其机制涉及神经和/或体液两大因素的调节作用,在临床上已有试用.
Ischemia/reperfusion injury （l/R） results in local and/or remote organ injury. Ischemic preconditioning （IPC） has been shown to protect organs against I/R. Remote ischemic preconditioning （RPC） is a new, easy and convenient strategy to protect organs against I/R by inducing a prior brief period （s） of I/R to an organ remote from that undergoing sustained injury. The mechanisms may involve in regulation of humoral and/or neural factors and this strategy has been applied in clinical trials.
出处
《国际麻醉学与复苏杂志》
CAS
2010年第3期254-257,共4页
International Journal of Anesthesiology and Resuscitation
关键词
远端预处理
机制
临床应用
Remote preconditioning
Mechanism
Clinical application
