水冷式微波消融系统实际功率的实验研究

An experimental study on the actual power of water-cooled percutaneous microwave coagulation

目的:通过冷循环微波天线对离体猪肝凝固的实验研究,探讨不同时间,实际功率的变化规律及凝固区的形态及范围。方法:应用MTC-3型冷循环微波天线,分别以不同时间和实际功率组合热消融30只新鲜离体猪肝,观察不同目的功率热消融前后实际功率的变化规律,以及在此条件下造成的组织损毁的范围和形态。结果:加大输出目的功率会增大目的功率与消融后功率的偏离,而消融后功率偏离随着凝固时间延长变化没有统计学意义。在加大输出目的功率的同时延长凝固时间,凝固范围显著增大,但以目的功率60～70W,凝固时间为15min时凝固区形态更接近球形。结论:微波的输出实际功率稳定及适度凝固时间是确保凝固范围前提,随着目的功率的增加,功率衰减也进一步增大。其中目的功率为60～70W,凝固时间为15min时所形成的凝固范围更趋向球形,此对肝癌热消融治疗取得稳定的效果会有较大指导意义。

Objective：To investigate the changes of actual power of percutaneous microwave coagulation and the size of coagulation area under different operating time and power through performing coagulation on pork liver in vitro using water refrigeration cycle microwave antenna. Methods：Thirty fresh pork livers underwent thermal ablation using MTC-3 water refrigeration cycle microwave antenna with different operating times and powers,respectively. The change of powers of thermal ablation and the size of the coagulation area were measured. Results：The deviation between the actual power and objective power was increased with the increase of objective power. While the deviation between the actual power and objective power showed no relation with the operating time. The size of coagulation area was increased with the increase of operating time and objective power. It was more likely that the coagulation area looked like a ball when the objective power was 60-70 W and the operating time was 15 min. Conclusion：The actual power of thermal ablation is important to the efficacy. With the increase of objective power, the attenuation of power is increased. The coagulation area shows as a ball with an objective power of 60-70 W and an operating time of 15 min. This study might provide evidence for thermal ablation used to treat liver cancer.