CA19-9联合多层螺旋CT在胰腺癌可切除性评估中的价值

CA19-9 Combined with Multi-slice Spiral CT Assessing Resectability of Pancreatic Cancer

目的:探讨CA19-9联合多层螺旋CT在胰腺癌可切除性评估中的价值。方法:将85例胰腺癌患者,根据治疗方式分为根治切除组、姑息手术治疗组与非手术治疗组,分析多层螺旋CT、CA19-9及二者联合在评估胰腺癌可切除性中的作用。结果:以CA19-9大于200作为评估不可切除的临界值,CA19-9评估胰腺癌可切除的准确率为65.6%,不可切除的准确率为56.6%。非手术治疗组CA19-9水平与根治切除组、姑息手术治疗组比较存在显著差异(P<0.05)。多层螺旋CT对判断胰腺癌可切除的准确率为71.4%,不可切除的准确率为77.4%。二者联合对胰腺癌可切除性评估的准确率为78.6﹪,不可切除的准确率为95.7﹪。结论:CA19-9联合多层螺旋CT可以更好的评估胰腺癌的可切除性。

Objective To investigate the value of CA19-9 combined with multi-slice spiral CT in assessing the resectability of pancreatric cancer. Methods Eighty-five patients diagnosed as pancreatic cancer were divided into radical resection group, palliative surgical treatment group, and non-surgical treatment group. The value of CT and CA19-9 or their combined use in assessing the resectability of pancreatic cancer were analyzed. CA19-9 level of 200 U/mL was used as a threshold to determine unresectability. Results The accuracy of CA19-9 for the prediction of respectability was 65.6%, that for the prediction of unresectability was 56.6%. Compared with the radical resection group and the palliative surgical treatment group, the levels of CA19-9 in non-surgical treatment group were significantly different. The accuracy of multi-slice spiral CT for the prediction of respectability was 71.4%, that for the prediction of unresectability was 77.%. The accuracy of CA19-9 combined with the multi-slice spiral CT in judging the resectability of pancreatic cancer was 78.65%, and for prediction of unresectability was 95.7%. Conclusion CA19-9 combined with multi-slice spiral CT has a greater value in the assessment of resectability of pancreatic cancer.