炎症反应综合征与脑梗死预后相关性分析

Correlation between Systematic Inflammatory Response Syndrome and Prognosis in Patients with Cerebral Infarction

目的:探讨全身炎症反应综合征(SIRS)对急性脑梗死预后的影响。方法:根据炎症反应综合征的诊断标准,将94例急性脑梗死患者分为SIRS组36例和非SIRS组58例,均于入院后第3天分别进行神经功能缺失评分、计算脑梗死面积和检测血中急性炎性蛋白,C-反应蛋白(CRP)浓度;3个月后统计死亡率。结果:测评结果显示,SIRS组患者神经功能缺失评分、脑梗死面积和血中CRP浓度均显著高于非SIRS组(P<0.01);3个月后死亡率也明显高于非SIRS组。结论:SIRS参与急性脑梗死的病情发展过程,可作为急性脑梗死病情的警示信号和预后判定指标。

Objective：To investigate the relationship between systematic inflammatory response syndrome（SIRS）and prognosis of patients with cerebral infarction（CI）.Methods：According to the diagnostic criteria of SIRS,94 cases of CI were divided into two groups：non-SIRS group（n=58）,SIRS group（n=36）.The neurological deficit score,mortality,cerebral infarction area and level of C-reactive protein（CRP）were determined.The values of items were statistically analyzed.Results：The results showed that the values of the neurological deficit score,mortality,cerebral infarction area and level of CRP in SIRS group were markedly increased as compared with non-SIRS group（P0.01）.Conclusion：The SIRS may be involved in the progression of the CI process.The SIRS was an important prognosis marker and warning signal of CI.