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有机磷农药的神经发育毒性研究进展 被引量：7

Research progress on neural development toxicity induced by organophosphorus pesticides
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摘要 本文综述了有机磷农药神经发育毒性的研究进展,包括有机磷农药神经发育毒性的证据、毒代动力学因素以及毒理学机制等。 In this paper,the neural development toxicity induced by organophosphorus pesticides especially its toxicity evidences,toxicokinetics factors and toxicological mechanism were well reviewed.
作者 韩俊艳 檀德宏 王军 纪明山
机构地区 沈阳大学生物与环境工程学院 沈阳药科大学生命科学与生物制药学院药理系 沈阳农业大学植物保护学院
出处 《中国工业医学杂志》 CAS 北大核心 2010年第3期199-202,共4页 Chinese Journal of Industrial Medicine
关键词 有机磷 农药 神经发育毒性 研究进展 organophosphate pesticide neural development toxicity research progress
分类号 R595.4 [医药卫生—内科学] R979.8 [医药卫生—药品]
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  • 1Grandjean P, Landrigan P J. Developmental neurotoxicity of industrial chemicals [J]. Lancet, 2006, 368 (9553): 2167-2178.
  • 2Guillette E A, Meza M M, Aquilar M G, et al. An anthropological approach to the evaluation of preschool children exposed to pesticides in Mexico [J]. Environ Health Perspect, 1998, 106 (6): 347-353.
  • 3Grandjean P, Harari R, Barr D B, et al. Pesticide exposure and stunting as independent predictors of neurobehavioral deficits in Ecuadorian school children [J]. Pediatrics, 2006, 117 (3) : 546-556.
  • 4Lizardi P S, O'Rourke M K, Morris R J. The effects of organophosphate pesticide exposure on hispanic children's cognitive and behavioral functioning [J]. J Pediatr Psychol, 2008, 33 (1): 91-101.
  • 5Rohlman D S, Arcury T A, Quandt S A, et al. Neurobehavioral performance in preschool children from agricultural and non-agricultural communities in Oregon and North Carolina [ J ]. Neurotoxicology, 2005, 26 (4): 589-598.
  • 6Young J G, Eskenazi B, Gladstone E A, et al. Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates [J]. Neurotoxicology, 2005, 26 (2): 199-209.
  • 7Levin E D, Addy N, Nakajima A, et al. Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats [J]. Dev Brain Res, 2001, 130 (1): 83-89.
  • 8Aldridge J E, Levin E D, Seidler F J, et al. Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembing animal models of depression [J]. Environ Health Perspect, 2005, 113 (5): 527-531.
  • 9Icenogle L M, Channelle C N, Paul B W, et al. Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation [ J ]. Neuroioxieol Teratol, 2004, 26 (1): 95-101.
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中国工业医学杂志
2010年 第3期

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