老年糖尿病患者红细胞膜Na^+-K^+-ATP酶活性及临床意义

Clinical significance of Na + K + ATPase in the membrane of red blood cell in aged diabetic patients

通过测定老年糖尿病患者红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶活性，发现糖尿病患者红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶活性明显低于对照组，血糖与Ｎａ＋－Ｋ＋－ＡＴＰ酶活性呈负相关（ｒ＝－０．６５６）。糖尿病伴神经病变患者神经传导速度明显减慢，Ｎａ＋－Ｋ＋－ＡＴＰ酶活性倾向低于不伴神经病变者。

Erythrocyte Na + K + ATPase activity were mesured in a group of aged diabetic patients.The result showed that erythrocyte Na + K + ATPase activity was significantly reduced in aged diabetic patients as compared with age matched control subjects.Blood glucose level was negatively correlated with Na + K + ATPase activity.And motor nerve conduction velocity(MNCV) was significantly decreased and Na + K + ATPase activity tended to reduce in the diabetic patients with neuropathy as compared with the patients without neruopathy.\;