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小脑变性相关蛋白2在难治性癫患者脑脊液及血液中的表达

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摘要 目的了解小脑变性相关蛋白2(CDR2)在难治性癫患者脑脊液及外周血中的表达情况。方法收集36例难治性癫患者的脑脊液和外周血,用酶联免疫吸附法(ELISA)检测其CDR2表达水平,并与39例对照者比较。结果难治性癫组脑脊液中CDR2的含量明显高于其外周血和对照组,差异有统计学意义(P<0.05),而难治性癫组外周血中CDR2含量与对照组无显著性差异(P>0.05)。结论 CDR2在难治性癫患者脑脊液中表达显著,因而检测CDR2在脑脊液中水平可能成为早期诊断难治性癫的一个重要指标。
出处 《卒中与神经疾病》 2010年第3期182-183,共2页 Stroke and Nervous Diseases
基金 湖北省卫生厅科研项目[NOJX3B44]
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参考文献7

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