弥可保治疗糖尿病自主神经病变的体会

Methycobal treatment of diabetic autonomic neuropathy Experience

目的：观察弥可保对糖尿病自主神经病变（DAH患者的治疗作用。方法：DAN病人160例，随机分为治疗组和对照组，治疗组予弥可保针500μg，静脉推注，每日2次，共2周；对照组：前2周，给予弥可保针500μg，肌肉注射，每日1次。两组后10周，均为口服，500μg，每日3次。结果：治疗组多汗、腹泻、便秘、排尿障碍、体位性低血压改善优于对照组；心脏自主神经测试治疗组优于对照组（P〈0．05）。且未见明显副作用。结论：大剂量弥可保对治疗DAN有一定疗效。

Objiective Observed Methycobal diabetic autonomic neuropathy （DAN） in patients with therapeutic effect. Methods DAN patients in 160 cases were randomly divided into treatment group and control group, treatment group I Methycobal pin 500 μg, intravenous injection, 2 times a day, a total of 2 weeks; control group： the first 2 weeks, to give Methycobal needle 500 μg, intramuscular injection, day 1. The two groups after 10 weeks were oral, 500 μg, 3 times a day. Results Treatment group, sweating, diarrhea, constipation, voiding dysfunction, orthostatic hypotension improvement than the control group; cardiac autonomic nerve testing the treatment group than the control group （P 〈0.05） And no obvious side effects. Conclusions High-dose treatment Mikebao DAN have a certain effect.