子宫颈电环切除术治疗子宫颈上皮内瘤变的疗效评价

Loop electrosurgical excision circumcise electrotome for treatment of cervical intraepithelial neoplasia

目的:观察子宫颈电环切除术(loop electrosurgical excision,LEEP)诊断及治疗子宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)的临床效果。方法:对经子宫颈脱落细胞学检查、阴道镜及子宫颈活检初步诊断为CIN的62例患者采用LEEP治疗,根据术前、术后病理变化及随访,判断LEEP的疗效。结果:LEEP术后病理诊断与阴道镜下点活检的病理诊断差异有统计学意义(P<0.01)。LEEP对患者治愈率达98.33%,对CIN 1、2者治愈率达100%,术后1年无CIN复发。结论:LEEP可提供完整的标本送病理检查,是诊断和治疗CIN的理想方法。

Objective：To investigate the effect of cervical loop electrosurgical excision（LEEP）in treatment of cervical intraepithelial neoplasia（CIN）.Methods：Sixty-two patients initially diagnosed as CIN by cervical cytology,colposcopy and cervical biopsy were treated by LEEP.The effects were determined according to the preoperative and postoperative pathological changes and the follow-up.Results：The results of pathological examination and colposcopy biopsy after LEEP were significantly different（P0.01）.The cure rate of LEEP surgery was 98.33%,and the cure rate for patients with CIN 1 and 2 reached 100%.No recurrence was found one year after the operation.Conclusions：LEEP can provide complete specimen for pathology examination.It is an ideal method for the diagnosis and treatment of CIN.