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高血压合并颈动脉粥样硬化斑块患者的血脂变化特征及他汀类药物干预效果

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摘要 【目的】探讨高血压合并颈动脉粥样硬化斑块患者的血脂变化特征及他汀类药物干预效果。【方法]2007年12月至2009年6月来本院门诊就诊的高血压患者,行颈动脉超声、血脂检查。颈动脉斑块患者予以阿托伐他汀20mg,每晚1次口服,6个月后复查血脂、颈动脉超声。【结果】颈动脉斑块者103例。斑块组的血LDL-C水平明显高于无斑块组(P〈0.01)。宽块组治疗后,TC、LDL-C有明显降低(P〈0.01)。治疗后各种类型斑块较前均有明显减小(P〈0.05)。【结论】高血压合并颈动脉斑块患者的血脂变化以低密度脂蛋白胆固醇增高为显著特征,他汀类药对缩小斑块疗效显著。
出处 《医学临床研究》 CAS 2010年第6期1092-1093,共2页 Journal of Clinical Research
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