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中国汉族人群Calpain-10基因UCSNP43多态性与2型糖尿病相关性的meta分析 被引量:3

Meta-analysis on the association of calpain-10 gene UCSNP-43 polymorphism with type 2 diabetes in Chinese Han population
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摘要 对中国汉族人群Calpain-10基因UCSNP43位点多态性与2型糖尿病的相关性进行meta分析.Calpain-10基因UCSNP43位点G等位基因、GG基因型可能是中国汉族人群2型糖尿病的危险因子;A等位基因、GA基因型可能为保护因子. To evaluate the association of ealpain-10 gene UCSNP-43 polyorphism with type 2 diabetes in Chinese Han population.Meta-analysis showed that calpain-10 gene UCSNP-43 polymorphism may be associated with type 2 diabetes in Chinese Han population.Allele G and genotypo GG may be risk factors for type 2 diabetes,while allele A and genotype GA may be the protective factors.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2010年第6期471-473,共3页 Chinese Journal of Endocrinology and Metabolism
关键词 CALPAIN-10基因 多态性 单核苷酸 糖尿病 2型 UCSNP43 META分析 Calpaio-10 gene Polymorphism,single nueleotide Diabetes mellitus,type 2 UCSNP43 Meta-analysis
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  • 1黄知敏,修玲玲,翁建平.钙激活蛋白酶-10基因相关的SNP等位基因频率和单体型频率在汉族人中的分布及其与胰岛素敏感性的关系[J].中国糖尿病杂志,2004,12(3):209-210. 被引量:3
  • 2纪立农.2型糖尿病遗传病因学研究的现状和展望[J].中国医学科学院学报,2006,28(2):278-283. 被引量:11
  • 3Song Y, Niu T, Manson JE, et al. Are variants in the CAPN10 gene related to risk of type 2 diabetes? a quantitative assessment of population and family-based association studies. Am J Hum Genet, 2004;74:208-222.
  • 4Baier LJ, Permana PA, Yang XL, et al. A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest,2000,106:R69-R73.
  • 5LI L, Sill Y,WANG X, et al. Single nueleotide polymorphisms in KATP channels muscular impact on type 2 diabetes[J]. Diabetes, 2005, 54:1592- 1597 .
  • 6HANNIS C L,BOERWINKLE E, CHAKRABORTY R, et al. A genome-wide search for non-insulin-dependent (type 2 ) diabetes genes reveals a major susceptibility locus on chromosome 2[J]. Nat Genet, 1996,13(2) : 101.
  • 7HORIKAWA Y,ODA N, COX N J, et al. Genetic variation in the gene coding calpain-10 is associated with type 2 diabetes mellitus [J]. Nat Genet,2000,26(2) : 163 - 175.
  • 8BALER L J, PERMANA P A, YANG X, et al. A calpain-10 gene polymorphism is associated with reduced muscle mrna levels and insulin resistance[ J ]. The Journal of clinical Investigation, 2000, 106(1 ) :69 - 72.
  • 9COX N J,FREIGGE M,NICOLAE D L,et al. Loci on chromosome2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans[ J ]. Nat Genet, 1999,21 (3) : 213.
  • 10Horikawa Y, Oda N, Cox N J, et al. Genetic variation in the Calpain-10 gene (CAPN10) isassociated with type 2 diabetes mellitus [J]. Nature Genet, 2000,26(2) :163-175.

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