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舒芬太尼在心脏术后静脉镇痛中的应用 被引量:4

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摘要 目的探讨舒芬太尼在心脏手术后静脉自控镇痛的疗效、安全性和相关不良反应。方法将60例ASAⅠ-Ⅲ级心脏手术患者随机平均分为两组,术毕行患者自控静脉镇痛(PCIA)。舒芬太尼(SF)组浓度为2μg/mL,芬太尼(F)组浓度为20μg/mL。两组背景剂量2 mL/h,PCA量0.5 mL/次,锁定时间15 min。比较术后镇痛镇静效果、不良反应及生命体征情况。结果两组镇痛效果都满意,SF组各个时段VAS普遍低于F组,但仅在术后12 h差异有统计学意义(P〈0.05)。SF组术后24 h内镇静评分达2分者多于F组,差异有统计学意义(P〈0.05)。两组术后恶心呕吐等不良反应发生率均较低,但恶心程度SF组评分明显少于F组,呕吐发生率明显低于F组(P〈0.05)。结论舒芬太尼应用于心脏术后静脉镇痛效果确切,安全系数高、不良反应发生率低,值得临床推广。
出处 《广东医学》 CAS CSCD 北大核心 2010年第12期1604-1606,共3页 Guangdong Medical Journal
基金 广东省汕头市重点科技计划项目(汕府科[2007]76-2)
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参考文献8

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二级参考文献7

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