沙眼衣原体感染与宫外孕关系的探讨

The correlation between chlamydial trachomatis infection and pregnancy ectopic

采用酶联免疫吸附试验（ＥＬＩＳＡ）和聚合酶链反应（ＰＣＲ）两种方法对４０例宫外孕患者血清中沙眼衣原体特异性ＩｇＧ抗体及宫颈分泌物中沙眼衣原体ＤＮＡ进行了检测。结果表明：宫外孕患者沙眼衣原体抗体阳性３３例（８２５％），ＰＣＲ法检测沙眼衣原体ＤＮＡ阳性１６例（４００％），其中１例沙眼衣原体抗体阴性而ＰＣＲ法阳性。另外，宫外孕患者与非淋菌性阴道炎患者沙眼衣原体感染的阳性率比较两种方法均无显著性差异（Ｐ＞００１）。因此，沙眼衣原体感染是宫外孕发生的主要病原体之一。

The article adopted two mothods of enzyme-linked immunosorbent assay(ELISA) and polymerase chain reaction (PCR) technology to detect the C.trachomatis special antibody IgG in serum and C.trachomatis DNA in cervical samples in 40 patients with pregnancy ectopic.Result shows:the positivity of ERLISA and PCR is 85%,42 5% respectively,ELISA negative but PCR positive has one case.We did not find no marked difference detween the C.trachomatis infeetion of patients with pregnancy ectopic and NGU.Our results demonstrat that C.trachomatis infcetion is a main factor inducing pregnancy ectopic.