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盐酸替罗非班用于行PCI的ST段抬高型急性心肌梗死患者的临床护理研究 被引量:5

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摘要 目的:探讨对ST段抬高急性心肌梗死(STEMI)患者行急诊经皮冠状动脉介入治疗(PCI)术中、术后应用盐酸替罗非班的效果、安全性及相关护理问题。方法:选择50例行急诊PCI的STEMI患者应用盐酸替罗非班(除有禁忌证),为盐酸替罗非班组。对照组为50例行急诊PCI的STEMI患者,未应用盐酸替罗非班,两组进行对照研究。观察两组患者心电图ST段下降幅度及出血情况,观察患者住院期间及出院后主要心脏不良事件(MACE,包括死亡、非致命性再梗死、靶血管再血管化治疗)的发生。结果:STEMI患者行PCI术应用盐酸替罗非班安全有效,能够较早改善STE-MI患者直接PCI术后冠脉微循环灌注状态,但增加出血倾向,未增加大出血发生率,临床工作中应严密观察用药后穿刺部位和全身出血情况,采取有效的护理措施。结论:对STEMI行直接PCI治疗护理者,除充分给予阿司匹林、氯吡格雷和肝素外,还应联合应用盐酸替罗非班,采取有效的护理措施,有助于减少急诊PCI的STEMI患者血栓栓塞和无复流、慢复流现象发生,降低术后不良心脏事件的发生,改善患者症状和预后,使早期行介入治疗的ACS患者明显受益。
作者 李京芳
机构地区 临沂市人民医院
出处 《齐鲁护理杂志》 2010年第6期44-45,共2页 Journal of Qilu Nursing
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  • 1童优利,刘聪华.触摸护理的临床效应[J].安徽医药,2005,9(7):552-553. 被引量:48
  • 2Rezkalla SH, Kloner RA. No-reflow phenomenon. Circulation, 2002,105 : 656-662.
  • 3Brener SJ, Barr LA, Burchenal JE, et al. Randomized, placebo-controlled trial of platelet glycoprotein Ⅱ b/Ⅲ a blockade with primary PTCA Organization and Randomized Trial ( RAPPORT ). Circulation, 1998,98 : 734-741.
  • 4Montalescot G, Barragan P, Wittenberg O, et al. For the ADMIRAL Investigators. Platelet glycoprotein Ⅱ b/Ⅲ a inhibition with coronary stenting for acute myocardial infarction. N Eng J Med, 2001, 344:1895-1903.
  • 5Stone GW, Grines CL, Cox DA, et al. Comparision of angioplasty with stenting, with or without abciximab, in acuete myocardial infarction. N Eng J Med, 2002, 346 : 957-966.
  • 6Neumann FJ, Blasini R, Schmitt C, et al. Effect of glycoprotein Ⅱ b/Ⅲ a receptor blockade on recovery flow and left ventricular function after the placement of coronary-artery stents in acute myocardial infction. Circulation, 1998, 98 : 2695-2701.
  • 7Petronioa AS, Rovai D, Musumeci G, et al. Effects of abciximab on microvascular integrity and left ventricular functional recovery in patients with acute infarction treated by primary coronary angioplasty. Euro Heart Journal, 2003, 24: 67-76.
  • 8The RESTORE Investigators. Effects of platelet glycoprotein Ⅱ b/Ⅲ a blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. Circulation, 1997, 96: 1445-1453.
  • 9Lincoff AM. Trial of platelet glycoprotein Ⅱ b/Ⅲ a receptor antagonists during percutaneous coronary revascularization. Am J Cardiol, 1998, 82:36-42.
  • 10Danzi GB, Sesana M, Capuano C, et al. Comparison in patients having primary coronary angioplasty of abciximab versus tirofiban on recovery of left ventricular function. Am J Cardiol, 2004, 94:35-39.

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