血小板输注后疗效观察

Globin chains haemoglobinopathies Effect of Platelet after Transfusion Observe

报道32例血液病和恶性肿瘤化疗导致血小板减少，有出血倾向的患分62次血小板输注后1h和24h血小板的变化，计算其血小板恢复率，并记录止血效果．结果随着血小板输注次数的增加，血小板输注后的有效率明显降低，止血效果不明显；测定几例血小板抗体，其含量随全血及血小板输注次数的增加而增高；发热与血小板输注效果间存在相关性（P＜0．05）；脾亢对血小板输注有影响，通过分析对血小板输注效果影响的因素，建议临床医生应尽量避免影响血小板输注效果的因素，合理地进行血小板输注．

We determined 32 patients' 62 times platelet concentrates aftertransfusion 1 hour and 24 hour thechange of platelet number and the effect of stop blooding. The patients were hematonosis or malignant tumor received chemotherapy results in platelet decrease and blood trend. Results were the more numbers of platelettransfused the lower their rate of effect. The results from examining some patients' platelet antibody shows theplatelet antibodies are relative to the transfusions. Fever and splenomegaly affect the effect of platelet transfusion. We recommend clinical doctor avoid above the factors as far as possible.