不同标准空腹血糖受损人群葡萄糖负荷后血糖代谢特征

Different standards impaired fasting glucose after glucose load glucose metabolism characteristics

目的:分析两种标准空腹血糖受损人群葡萄糖负荷后血糖代谢特点。方法:对3828名40岁以上居民进行流行病学调查,对空腹血糖≥5.6mmol/L者行75g葡萄糖负荷试验,据不同空腹血糖受损诊断标准分析负荷后2h血糖代谢情况。结果:在以空腹血糖为6.1mmol/L为切点诊断的245例空腹血糖受损(IFG)人群中,糖耐量减低(IGT)的患病率为41.22%,女性(25.71%)高于男性(15.51%);2型糖尿病(T2DM)患病率为20.82%,女性(11.84%)高于男性(8.98%)。在以空腹血糖为5.6mmol/L为切点诊断的627例空腹血糖受损人群中,糖耐量减低的患病率为37.00%,女性(23.76%)高于男性(13.23%);2型糖尿病患病率为13.88%,女性(9.52%)高于男性(4.63%)。结论:以空腹血糖为5.6mmol/L和6.1mmol/L为切点诊断的空腹血糖受损人群葡萄糖负荷后2h血糖代谢异常率分别为50.88%和62.04%,患病率女性均高于男性。

Objective：To analyze the metabolism characteristics about blood glucose after glucose load（2hPG） in different impaired fasting glucose populaton（IFG）.Methods：Across-sectional study was conducted on 3 828 residents above 40 years old.The oral glucose tolerance test（OGTT,75 g glucose） was administrated for people whose fasting blood glucose（FPG） ≥5.6 mmol/L.To analyze metabolism characteristics about 2 hPG in different IFG.Results：The prevalence of IGT in IFG（FPG≥6.1 mmol/L） population was 41.22%,it was higher in female（25.71%） than male（15.51%）,The prevalence of T2DM was 20.82%,it was higher in female（11.84%） than male（8.98%）.The prevalence of IGT in IFG（FPG ≥5.6 mmol/L） population was 37%,it was higher in female（23.76%） than male（13.23%）,The prevalence of T2DM was13.88%,it was higher in female（9.52%） than in male（4.63%）.Conclusion：The prevalence of abnormal 2hPG in different IFG population are 50.88% and 62.04%,it is higher in female than male.