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RNAi技术沉默Livin基因在肿瘤中的研究进展 被引量:2

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出处 《福建医药杂志》 CAS 2010年第3期83-85,共3页 Fujian Medical Journal
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  • 1周晟,万婕,刘聪,阮秋蓉,李娜萍.凋亡抑制基因livin与survivin在乳腺癌中的表达差异[J].中国组织化学与细胞化学杂志,2006,15(5):554-558. 被引量:13
  • 2Igney FH, Krammer PH. Death and anti-death : turnout resistance to apoptosis. Nat Rev Cancer, 2002, 2 : 277-288.
  • 3Kasof GM, Comes BC. Livin, a novel inhibitor of apoptosis protein family member. Biol Chem, 2001, 276:3238-3246.
  • 4Yagihashi A, Ohmura T, Asanuma K, et al. Detection of autoantibodies to survivin and livin in sera from patients with breast cancer. Clin Chim Acta, 2005, 362:125- 130.
  • 5Mello CC, Conte D Jr. Revealing the world of RNA interference. Nature, 2004, 431: 338-342.
  • 6Tanabe H, Yagihashi A, Tsuji N, et al. Expression of survivin mRNA and livin mRNA in non-small-cell lung cancer. Lung Cancer, 2004, 46: 299-304.
  • 7Gazzaniga P, Gradilone A, Giuliani L, et al. Expression and prognostic significance of LIVIN, SURVIVIN and other apoptosis- related genes in the progression of superficial bladder cancer. Ann Oncol, 2003, 14:85-90.
  • 8Crnkovic-Mertens I, Hoppe-Seyler F, Butz K. Induction of apoptosis in Tumor cells by siRNA mediated silencing of the livin/ ML-IAP/KIAP gene. Oncogene, 2003, 22: 8330-8336.
  • 9Crnkovie-Mertens I, Semzow J, Hoppe-Seyler F, et al. Isoformspecific silencing of the Livin gene by BNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa ceils. J Mol Med, 2006, 84: 232-240.
  • 10Overhoff M, Alken M, Far RK, et al. Local RNA target structure influences siRNA efficacy: a systematic global analysis. J Mol Biol, 2005, 348: 871-881.

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