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吉西他滨联合顺铂一线治疗晚期非小细胞肺癌60例临床观察 被引量:1

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摘要 目的观察吉西他滨(GEM)与顺铂联合一线治疗60例晚期非小细胞肺癌(NSCLC)的近期疗效及副作用。方法吉西他滨1000mg/m2静脉滴注,第1、8天各1次;顺铂25mg/m2,第2~4天静脉滴注,每21天为一周期,并辅以格拉司琼预防消化道反应、集落细胞刺激因子预防骨髓抑制。治疗每2个周期评价疗效。结果完全缓解(CR)0例、部分缓解(PR)17例、稳定(SD)22例、进展(PD)21例,总有效率(CR+PR)17例(28.3%),疾病控制率(CR+PR+SD)39例(65.0%)。主要不良反应为骨髓抑制和恶心呕吐。结论吉西他滨联合顺铂治疗非小细胞肺癌安全、有效,是较理想的治疗方案。
出处 《福建医药杂志》 CAS 2010年第3期127-128,共2页 Fujian Medical Journal
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