摘要
目的：研究血清可溶性白细胞介素2受体（sIL-2R）水平在检查乙肝病毒不同类型感染中的意义。方法：应用ELISA方法检测42例正常人及228例乙肝病毒感染者血清中sIL－2R水平。并从感染者中筛选出3组进行比较，A组（大三阳，HBsAg，HBcAb，HBeAg（＋））；B组（小三阳，HBsAg，HBcAb，HbeAb（＋））；C组（HBsAg（＋））。结果：228例感染者血清中sIL－2R水平较正常人都明显增高（P＜0．01）。且A，B两组sIL－2R水平与正常人相比也差异显著（P＜0．05）。各组之间比较，仅A与C组之间有显著差异（P＜0．01）。结论：提示检测血清中sIL－2R可作为乙肝病毒感染者病情变化和预后判断的监测指标。
Purpose: Detecting the level of soluble interleukin-2 receptors (sIL-2R) in serum and evaluating its in different hepstitis B. Methods: The levels were detected by using ELISA in serum from 228 cases of hepatitis B virus infection and 42 cases of the normal control. The patients were divided into three groups. The group A (HBsAg (+ ), HBcAb (+) and HBeAg(+)), the group B (HBsAg (+), HBcAb(+) and HBeAb (+) and the group C (HBsAg (+)). Results: Theresults showed that the levels of sIL-2R were increased in serum from 228 patients obviously compared with the normal control (P<0. 01), there was also obvious difference between A and C (P<0. 01). Conclusions: The level of sIL-2R in serum may be as an indication to monitor the change of the HB patients and their prognosis.
出处
《地方病通报》
1999年第1期25-27,共3页
Endemic Diseases Bulletin
关键词
乙肝型炎病毒
乙型肝炎
免疫学
ELISA
SIL-2R
Hepatitis B virus (HBV)
Soluble interleukin-2 receptors (sIL-2R )
Immunologic test
ELISA
