龋活跃儿童和无龋儿童唾液抗变链抗体水平

Level of anti-streptococcus mutans surface protein antigen S-IgA class antibodies in saliva from caries-free children or caries-active children

目的研究龋活跃儿童和无龋儿童唾液特异性抗体水平，了解机体免疫状况与龋病发生的关系。方法使用酶联免疫吸附实验（ELISA）方法，对30名龋活跃儿童和20名无龋儿童唾液中抗变形链球菌表面蛋白抗原的SIgA抗体进行测定。结果无龋儿童唾液中抗特异性抗体水平明显高于龋活跃儿童。结论提示无龋儿童可能是因其唾液中存在的高水平特异性抗体抑制了龋病的发生。

in the paper we analtysed the level of specific anti-Ag Ⅰ /Ⅱ in saiva from 50 children whowere caries-free (n= 20) or cariescive(n=30). The results indicated that the specific anti-Ag Ⅰ /Ⅱ SIgA antibodies of cariess-free children are obviously higher than of cariesactive children (P < 0. 05).Those suggested that development and extent of caries was ctheely related to the condition of body localimmune system.