变应性真菌性鼻-鼻窦炎1例并文献复习

Allergic fungal rhinosinusitis:one case and literature review

目的:探讨变应性真菌性鼻-鼻窦炎(AFRS)的临床特点与治疗。方法:结合文献复习报告1例AFRS。鼻窦CT表现为云雾状高密度影,鼻窦分泌物涂片可见Charcot-Leyden结晶及真菌菌丝。结果:AFRS患者经鼻内镜手术及激素、局部抗真菌药物治疗痊愈。结论:AFRS的诊断主要依靠病史、特征性的CT表现、病理学、真菌学及免疫学检查。手术、全身的免疫治疗、局部抗真菌药物以及长期随诊在AFRS治疗过程中十分重要。

Objective：To investigate the presentation and the management of allergic fungal rhinosinusitis（AFRS）.Method：One case of AFRS was reported and the relevant literatures were reviewed.CT scan showed high-attenuation like ＂cloud and mist＂,Charcot-Leyden crystals and fungal hyphae were found in nasal smear.Result：The patient recoved after a combined therapy of endoscopic sinus surgery,steroids and local antifungal drugs.Conclusion：The diagnosis of AFRS depends on history,the characteristics of CT scanning,pathology,mycologic and immunologic test.The management of surgery,systemic immunotherapy,local antifungal drugs and longer follow up is very important.