弥漫性大B细胞淋巴瘤中Bcl-2基因重排与蛋白表达的关系探讨
摘要
目的探讨Bcl-2在弥漫性大B细胞淋巴瘤(diffuse large B—cell lymphoma,DLBCL)不同类型中的表达及意义。方法应用免疫组织化学S—P法检测60例弥漫性大B细胞淋巴瘤标本中Bcl-2蛋白的表达水平;同时行RT—PCR检测外周血Bcl-2/IgH的表达水平。结果60例DLBCL中,Bcl-2阳性率分别为61.67%(37/60);Bcl-2/IgH的阳性表达12例(12/60)。结论Bcl-2有望成为DLBCL亚分类的指标。
出处
《实用肿瘤学杂志》
CAS
2010年第3期260-263,共4页
Practical Oncology Journal
基金
云南省教育厅科学研究基金项目(NO.07C10461)
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