遗传性皮肤色素异常的分子遗传学研究进展

Advances in Molecular Genetics of Dyschromatosis Hereditaria

遗传性皮肤色素异常在临床上是组异质性疾病，包括数十种疾病。临床分类：不很清楚，疾病的分子基础也不清楚，近年来，在遗传性皮肤色素异常的分子遗传学研究方面，我国学者做了一些重要的原创性工作，以下就遗传性皮肤色素异常的分子遗传学基础和临床诊断的进展做一综述。

Dysehromatosis hereditaria was a group of genetically heterogeneous disorders. Nearly 10 disorders were included in this entity. Most of them were monogenic diseases. The genetic basis and clinical categorization remain unclear, Recently,reseachers in our courtry have made greater progress in the study. This article reviews advances on molecular basis and clinical diagnosis for dyschromatosls hereditaria.