血液灌流在急性重度有机磷中毒的临床分析及护理

Use of hemoperfusion in severe acute organophosphorus pesticide poisoning and the nursing

目的:探讨应用血液灌流(hemoperfusion,HP)抢救重度急性有机磷农药中毒(acute organicpesticide poisoning,AOPP)患者的疗效及护理。方法:对我院自2000年1月～2006年1月收治的76例重度急性有机磷中毒患者随机分为血液灌流组50例(HP组),非血液灌流组26例(对照组),两组患者均予阿托品、解磷定等综合治疗,HP组在此基础上加用血液灌流或血液灌流+血液透析治疗,比较两组疗效。结果:HP组平均住院时间,胆碱脂酶活力恢复时间均短于对照组(P<0.05)。HP组病死率明显低于对照组(P<0.05)。结论:血液灌流或血液灌流+血液透析能有效清除体内的毒物,提高抢救成功率,在治疗时加强血液灌流的各项护理工作,是顺利进行血液灌流的关键。

Objective： To explore the effects of hemoperfusion（HP） on acute organophosphorus pesticide poisoning（AOPP）,and the patients＇ nursing.Methods： A total of 76 AOPP patients who were admitted to our hospital during January 2000 to January 2006 were randomly divide into HP group（50 cases and non-HP group（26 cases）.Both groups were given atropine and pralidoxime comprehensive therapy;the HP group was also given an extra treatment of HP and hemodialysis.Therapeutic effects of the two groups were compared.Results： Hospital stay and cholinesterase rejuvenation time of the HP group was significant shorter than that of the non-HP group（P0.05）;and the mortality of the HP group was lower than that of the latter group（P0.05）.Conclusions： HP or HP plus hemodialysis therapy can raise the rescue rate by eliminating toxicology in the body effectively;specifically the ancillary nursing work is the key to successful rescue.